Reduction of Tear-Drop Poikilocytes in a Case of Myelofibrosis Following Splenectomy
نویسندگان
چکیده
Myelofibrosis is a chronic myeloproliferative disorder characterised by splenomegaly, leukoerythroblastic anaemia, tear-drop poikilocytosis and marrow fibrosis. Splenectomy is indicated for patients requiring frequent transfusions or massive splenomegaly causing distressing symptoms and severe thrombocytopenia secondary to hypersplenism. A 56 year-old lady diagnosed to have primary myelofibrosis in year 2000 was referred to HUKM for further management of her increasing requirement of blood transfusion and Address for correspondence and reprint requests: Dr Chooi-Fun Leong, Haematologi Unit, Department of Pathology, Faculty of Medicine UKM, Jalan Yaakob Latif, Bandar Tun Razak, 56000 Cheras, Kuala Lumpur. Email: [email protected]
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